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Incidence of adverse reactions
| Variable | Patients (N = 39) | |
|---|---|---|
| Any grade, N (%) | Grade 3 or 4, N (%) | |
| Leukopenia | 27 (73.0) | 0 (0) |
| Granulocytopenia | 29 (78.4) | 0 (0) |
| Thrombocytopenia | 6 (16.2) | 1 (2.7) |
| Elevated transaminase | 9 (24.3) | 0 (0) |
| Hand-foot syndrome | 9 (24.3) | 0 (0) |
| Stomatitis | 14 (37.8) | 0 (0) |
| Fatigue | 20 (54.1) | 0 (0) |
| Proteinuria | 4 (10.8) | 0 (0) |
| Gastrointestinal hemorrhage | 2 (5.4) | 1 (2.7) |
| Hypertension | 10 (27.0) | 1 (2.7) |
| Neurotoxicity | 10 (27.0) | 0 (0) |
| Gastrointestinal perforation | 1 (2.7) | 1 (2.7) |
