Skip to main content
. 2021 Jun 14;22:220. doi: 10.1186/s12882-021-02433-8

Table 3.

Clinical characteristics of six cases of coexisting AAV and HIT, including this case

Literature Age Sex Type of ANCA Organ injury Treatment for AAV Onset of HIT Type of heparin Thrombotic event Treatment for HIT
Roe et al. [31]. 65 M PR3

Crescentic glomerulonephritis

Pulmonary hemorrhage

mPSL pulse,

PSL, CY

Hemodialysis

9 days after the start of hemodialysis Unfractionated heparin

Deep venous

thrombosis

Danaparoid
Kaneda et al. [32]. 91 F MPO

Kidney dysfunction

Pulmonary hemorrhage

mPSL pulse,

PSL,

Hemodialysis

13 days after the start of hemodialysis Unfractionated heparin N/A Argatroban
Mandai et al. [33]. 40 M MPO

Crescentic glomerulonephritis

Interstitial pneumonia

mPSL pulse,

PSL, CY, PE,

Hemodialysis

5 days after the start of hemodialysis Unfractionated heparin Clotting in hemodialysis catheter Argatroban
Thong et al. [34]. 71 M PR3 Kidney dysfunction

mPSL pulse,

PSL, CY,

Hemodialysis

15 days after the start of hemodialysis Unfractionated heparin Circuit and catheter clotted Argatroban
Nonaka et al. [35]. 87 F MPO Kidney dysfunction

PSL

Hemodialysis

8 days after the start for prevention of deep vein thrombosis Unfractionated heparin Deep venous thrombosis Argatroban
This case 76 M MPO

Crescentic glomerulonephritis

Interstitial pneumonia

mPSL pulse,

PSL, CY

Hemodialysis

14 days after the start of hemodialysis Unfractionated heparin

cerebral infarction

Clotting in hemodialysis catheter

Aargatroban

ANCA Anti-neutrophil cytoplasmic antibody, AAV anti-neutrophil cytoplasmic antibody-associated vasculitis, HIT heparin-induced thrombocytopenia, PR3 proteinase 3, MPO myeloperoxidase, mPSL methylprednisolone, PSL prednisolone, CY cyclophosphamide, PE plasma exchange