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. 2021 Jun 15;14:44. doi: 10.1186/s13047-021-00477-5

Table 2.

Neurovascular foot assessments

Median TCC duration
Foot assessment/variable Total
(N = 27)
<  4 months
(n = 12)
>  4 months
(n = 15)
OR (95% CI) P-value*
Peripheral neuropathya 26 (96.3) 11 (91.7) 15 (100.0) 0.42 (0.27 to 0.66) 0.444
 Left
  0/3, n (%) 24 (88.9) 11 (84.6) 13 (92.9)
  1/3, n (%) 1 (3.7) 0 (0) 1 (7.1)
  2/3, n (%) 1 (3.7) 1 (7.7) 0 (0)
  3/3, n (%) 1 (3.7) 1 (7.7) 0 (0)
 Right
  0/3, n (%) 24 (88.9) 11 (84.6) 13 (92.9)
  1/3, n (%) 1 (3.7) 1 (7.7) 0 (0)
  2/3, n (%) 0 (0) 0 (0) 0 (0)
  3/3, n (%) 2 (7.4) 1 (7.7) 1 (7.1)
Peripheral arterial diseaseb 9 (33.3) 4 (33.3) 5 (33.3) 1.00 (0.20 to 5.00) >  0.99
 Pedal pulses
  0/4, n (%) 1 (3.7) 1 (7.7) 0 (0)
  1/4, n (%) 1 (3.7) 0 (0) 1 (7.1)
  2/4, n (%) 4 (14.8) 2 (15.4) 2 (14.3)
  3/4, n (%) 1 (3.7) 0 (0) 1 (7.1)
  4/4, n (%) 19 (70.4) 10 (76.9) 9 (64.3)
 Mean ABPI (SD)
  Left 1.15 (0.20) 1.11 (0.21) 1.20 (0.20)
  Right 1.11 (0.23) 1.08 (0.15) 1.16 (0.33)
 Mean TBPI (SD)
  Left 0.82 (0.15) 0.79c 0.83 (0.21)
  Right 0.66 (0.17) 0.78c 0.53c
 Mean systolic toe pressure (SD)
  Left 105.4 (11.6) 118c 102.3 (10.6)
  Right 99.0 (13.9) 109c 95.7 (15.0)

Data are n (%) or mean (SD), unless otherwise specified. Percentages may not add up to 100%, as they are rounded to the nearest percent

ABPI, ankle-brachial pressure index; SD, standard deviation; TBPI, toe-brachial pressure index; TCC, total contact casting

*Significant difference between ‘< 4 months’ and ‘> 4 months’ median TCC duration groups, p < 0.05

aPeripheral neuropathy was defined as a monofilament score < 3/3 either foot

bPeripheral arterial disease was defined as absence of ≥2 pedal pulses, TBPI ≤0.6, and/or ABPI ≤0.9 either foot

Maximum missing data were for right TBPI involving 25 participants overall (92.6%). Missing data were for pedal pulses (n = 1), ABPI (n = 15), left TBPI (n = 24), right systolic toe pressure (n = 23), and left systolic toe pressure (n = 20)

cAs a result of missing data pertaining to toe systolic pressures, ankle systolic pressures and/or TBPI scores, data reported are the raw data for one participant only. Therefore, mean (SD) were unable to be calculated and reported