Table 1.
Case Characteristics of the Community-Acquired Clostridium difficile Infection Cohort
| Nonuse | Current Use of PPIs | 0–6 Months After Treatment Cessation | 6–12 Months After Treatment Cessation | |
|---|---|---|---|---|
| Number of CA-CDI events | 2172 | 964 | 324 | 123 |
| Male sex, n (%) | 845 (39) | 341 (35) | 130 (40) | 41 (33) |
| Age, mean (SD), years | 56.6 (22.0) | 71.6 (16.3) | 65.3 (19.5) | 59.1 (21.2) |
| Calendar year, n (%) | ||||
| 2010 | 386 (18) | 143 (15) | 40 (12) | 15 (12) |
| 2011 | 568 (26) | 238 (25) | 72 (22) | 34 (28) |
| 2012 | 567 (26) | 294 (30) | 100 (31) | 40 (33) |
| 2013 | 651 (30) | 289 (30) | 112 (35) | 34 (28) |
| Recent use of corticosteroids, n (%) | 126 (6) | 120 (12) | 34 (10) | 9 (7) |
| Recent use of antibiotics, n (%) | 1128 (52) | 554 (57) | 178 (55) | 66 (54) |
| Recent hospitalization, n (%) | 660 (30) | 443 (46) | 137 (42) | 45 (37) |
Abbreviations: CA-CDI, community-acquired Clostridium difficile infection; PPI, proton-pump inhibitor.