Figure 2.

Estimated prevalence of tuberculosis (TB) among adults aged ≥15 years in an urban Ugandan community. The study’s primary measure (top bar) is compared to multiple alternative definitions and to the Ugandan national prevalence survey estimate for urban areas, as detailed in Supplementary Table 1. The estimated prevalence increased slightly when adjusted for the age and sex of those screened, because younger men were both more likely to have TB and more likely to be missed by screening (Supplementary Table 3), and decreased slightly if the 70 consenting adults who were unable to produce sputum (0.6%) and the 199 with an invalid or missing Xpert MTB/RIF Ultra result (1.7%) were included. Exclusion of cases who were trace positive but culture negative shifted prevalence estimates more significantly. Conversely, including an estimate of the number who were Ultra negative but would have been culture positive increased the prevalence estimate dramatically, but our small sample size of cultures in Ultra-negative individuals is reflected in the large uncertainty around this estimate. Error bars indicate 95% confidence intervals.