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. 2020 Apr 8;72(12):2154–2163. doi: 10.1093/cid/ciaa397

Figure 3.

Figure 3.

Diagnostic performance visualized with ROC curves of the logistic regression analysis for AIN3+ detection: univariable regression (LOOCV) for the 6 individual methylation markers (ASCL1, LHX8, SST, WDR17, ZIC1, ZNF582) and multivariable regression (LOOCV) for the optimal marker panel (ASCL1, SST, ZNF582). Endpoint: AIN3+ (AIN3 and anal SCC). Abbreviations: AIN2–3, anal intraepithelial neoplasia (grade 2–3); AUC, area under the ROC curve; LOOCV, leave-one-out cross-validated; ROC, receiver operating characteristic.