. 2021 May 27;4(3):1136–1148. doi: 10.1021/acsptsci.1c00033

Table 2. IC₅₀’s and ED₅₀’s for HDAC 1, 2, and 3 Specific Inhibitors (Figure 2A Compounds)^a.

Color coded boxes indicate the specificity of the compound. Green borders, low IC₅₀ values (μM); and red, no specific inhibitory activity. Superscripts indicate the method for IC₅₀ value determination. IC₅₀ values provided by Reaction Biology Corporation (method a) or KDAc Therapeutics (method c). Mean ED₅₀’s in μM (and ranges) for reduction of cholesterol accumulation for each compound.

Table 2. IC50’s and ED50’s for HDAC 1, 2, and 3 Specific Inhibitors (Figure 2A Compounds)a.

Table 2. IC₅₀’s and ED₅₀’s for HDAC 1, 2, and 3 Specific Inhibitors (Figure 2A Compounds)^a.