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. 2021 Jun 12;7(8):FSO735. doi: 10.2144/fsoa-2021-0045

Table 1. . Demographic and clinical characteristics that differ across ABO blood type groups.

Blood type (sample size)
A (143)
AB (18)
B (45)
O (267)
Main effect
Pairwise post hoc comparisons (p-values)
Demographics n (%) n (%) n (%) n (%) p-value A-AB A-B A-O AB-B AB-O B-O
Hispanic ethnicity 102 (71.3%) 9 (50%) 26 (57.8%) 206 (77.2%) 0.006 0.463 0.463 0.476 0.779 0.105 0.061
Age§, mean (SD) 64.2 (16.5) 64.83 (20.3) 55.73 (18.1) 60.32 (16.0) 0.011 0.999 0.015 0.110 0.200 0.678 0.315
Comorbidities n (%) n (%) n (%) n (%) p-value A-AB A-B A-O AB-B AB-O B-O
CKD or ESRD 37 (25.9%) 9 (50%) 7 (15.6%) 69 (25.8%) 0.047 0.255 0.581 >0.999 0.071 0.255 0.581
Initial lab values Mean (SD) Mean (SD) Mean (SD) Mean (SD) p-value A-AB A-B A-O AB-B AB-O B-O
Peak creatinine¶‡
(Cr, 0.5–1.0 mg/dl)
2.06 (2.29) 3.8 (3.53) 1.4 (1.73) 2.28 (3.09) 0.018 0.062 0.513 0.872 0.012 0.115 0.205
Peak neutrophils#‡
(neutrophils %, 38–74%)
83.4 (9.8) 88.52 (4.71) 81.69 (8.9) 84.96 (9.13) 0.020 0.134 0.696 0.360 0.046 0.411 0.123
Mean lymphocytes#‡
(lymphocytes %, 16–48%)
14.35 (7.7) 11.06 (4.38) 17.61 (8.46) 14.94 (8.02) 0.019 0.364 0.074 0.886 0.019 0.200 0.154
Monocytes#
(monocytes %, 4.9–12.5%)
6.97 (3.99) 5.29 (2.97) 6.03 (2.77) 6.02 (3.42) 0.038 0.248 0.406 0.048 0.881 0.841 >0.999
Peak D-dimer (<500 ng/ml)††‡ 2394.68 (2755.2) 3342.95 (3034.84) 1491.12 (1994.32) 2687.8 (2799.17) 0.040 0.559 0.260 0.775 0.099 0.789 0.049

Main effect p-values indicate overall comparison across all blood type groups. Only significant main effects have respective pairwise comparisons with p-values shown.

Specified measures were not from initial labs and represent either peak or mean across entire hospitalization.

§

One patient missing data, n = 472 for age.

Metabolic panel n = 464–465.

#

Blood count n = 471–473.

††

Inflammatory markers n = 395–408.

CKD: Chronic kidney disease; ESRD: End-stage renal disease; SD: Standard deviation.