Table 2. . Study outcomes by blood group.
Outcomes | A (n = 143) | AB (n = 18) | B (n = 45) | O (n = 267) | Main effect |
p-value (A is reference) | Adj‡ p-value | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n (%) | OR† (95% CI) | n (%) | OR† (95% CI) | n (%) | OR† (95% CI) | n (%) | OR† (95% CI) | p-value† | AB | B | O | ||
ICU | 61 (42.7%) | Ref | 9 (50%) | 1.34 (0.5–3.6) | 15 (33.3%) | 0.67 (0.3–1.3) | 122 (45.7%) | 1.13 (0.8–1.7) | 0.424 | 0.643 | |||
Intubation | 47 (32.9%) | Ref | 7 (38.9%) | 1.3 (0.5–3.5) | 10 (22.2%) | 0.58 (0.3–1.2) | 85 (31.8%) | 0.95 (0.6–1.5) | 0.477 | 0.590 | |||
Death | 34 (23.8%) | Ref | 7 (38.9%) | 2.04 (0.7–5.6) | 4 (8.9%) | 0.31 (0.1–0.9) | 55 (20.6%) | 0.83 (0.5–1.4) | 0.037 | 0.172 | 0.038 | 0.457 | 0.197 |
Median§ (IQR) | HR¶ (95% CI) | Median§ (IQR) | HR¶ (95% CI) | Median§ (IQR) | HR¶ (95% CI) | Median§ (IQR) | HR¶ (95% CI) | LOS§p-value | Surv¶p-value | Adj#p-value | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
LOS# | 9 (5.0–17.0) | Ref | 9 (5.3–15.3) | 0.66 (0.4–1.2) | 8 (4.0–17.0) | 1.42 (1.0–2.0) | 10 (6.0–21.0) | 0.95 (0.8–1.2) | 0.139 | 0.0695 | 0.1446 |
OR and 95% CI calculated from independent, univariable logistic regression to identify effects of blood type on ICU admissions, intubation and death.
Adjusted p-values are from tests of conditional associations of blood type on each outcome in a multivariable logistic regression model including Hispanic ethnicity, age and CKD.
Median LOS was compared using a Kruskal–Wallis test.
HR and 95% CI’s result from a univariable Cox proportional hazards model with blood type as an independent predictor of survival to discharge, censoring on in-hospital death, with p-value indicated.
The adjusted p-value is from a multivariable Cox proportional hazards model to test conditional associations of blood type accounting for Hispanic ethnicity, age and CKD.
CKD: Chronic kidney disease; HR: Hazard ratio; ICU: Intensive care unit; IQR: Interquartile range; LOS: Length of hospital stay; OR: Odds ratio.