Figure 4. Downregulation of FOXP2 targets Nrp2 and Efnb2 in Foxp2‐deficient lymphatic vessels.

• A, B
  Whole‐mount immunofluorescence (A) and quantification of NRP2 staining intensity (B) in P6 mesenteric lymphatic vessels of Foxp2^{flox /−} ;Tie2‐Cre and littermate control mice (n = vessels [mice], as indicated).
• C, D
  RNAscope‐based whole‐mount in situ hybridization (C) and quantification of Efnb2 transcript levels (D) in P7 mesenteric lymphatic vessels of Foxp2^{flox /−} ;Tie2‐Cre and littermate control mice (n = vessels [mice], as indicated).

Data information: In (B, D), data are presented as mean ± SD. P, Student's t‐test. Scale bar: 100 µm.

Source data are available online for this figure.