Table 2.
Outcomes by Adequate or Inadequate Empiric Therapy: Observed Data and Univariate Assessmenta
| Total (n = 39 203) | SARS-CoV-2 Positive (n = 3674) | SARS-CoV-2 Negative (n = 35 529) | ||||
|---|---|---|---|---|---|---|
| Outcome | AET | IET | AET | IET | AET | IET |
| No. (%) | 21 098 (55.9) | 17 295 (44.1) | 1922 (52.3) | 1752 (47.7) | 19 986 (56.3) | 15 543 (43.7) |
| Mortality, No. (%) | 1475 (6.7) | 1576 (9.1) | 433 (22.5) | 509 (29.1) | 1042 (5.2) | 1067 (6.9) |
| Mean hospital LOS (SD), d | 9.1 (9.0) | 11.6 (11.0) | 14.7 (14.1) | 18.0 (15.8) | 8.6 (8.2) | 10.9 (10.1) |
| Mean ICU LOS (SD), d | 6.9 (8.6) | 8.5 (9.9) | 14.0 (13.8) | 14.8 (13.7) | 5.8 (7.0) | 7.3 (8.5) |
Abbreviations: AET, adequate empiric therapy; ICU, intensive care unit; IET, inadequate empiric therapy; LOS, length of stay; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
a P < .001 for IET vs AET for all outcomes except for SARS-CoV-2-positive ICU LOS (P = .265).