Skip to main content
. 2021 Jun 11;13(1):1932230. doi: 10.1080/19420862.2021.1932230
ACSINS Affinity-capture self-interaction nanoparticle spectroscopy
ADA Anti-drug antibodies
CDR Complementarity-determining region
CL Clearance
Fc Crystalizable fragment
FcRn Neonatal Fc receptor
Fv Variable fragment
Fvcharge5.5 Net antibody Fv charge at pH 5.5
HI_sum Hydrophobic index along three CDRs
IgG Immunoglobulin G
mAb Monoclonal antibody
MMAE Monomethyl-Auristatin E
Patch_cdr_hyd Surface area of the hydrophobic patches near the CDRs
pI Isoelectric point
pI_3D Structure-based pI prediction
pI_seq Sequence-based pI prediction
PK Pharmacokinetics
PSR Poly-specificity reagent
TAP Therapeutic antibody profiler
TMDD Target-mediated drug disposition