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. 2021 Jun 12;28(1):1120–1131. doi: 10.1080/10717544.2021.1934189

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Effects of CD–Cur–CANPs on the inflammation, intestinal tight junctions and colonic microbiota composition in mice with colitis. Levels of inflammatory cytokines (IL-1β, IL-6, and TNF-α) in colon were determined by ELISA kits (A) and qPCR (B). The protein expression of ZO-1 and occluding were assessed using western blot (C) and quantitative analyzed (D). GAPDH was used to normalize the protein level and the relative ratio to control group. The relative abundance of microbiota species was determined by qPCR (E). Compared to the control group, ^#p < .05, ^##p < .01, ^###p < .001. Compared to the DSS group, *p < .05, **p < .01; na: no significance.