Table 1.
Histology after retinal ischemia
Mean number of cells in RGC layer | |
---|---|
Scrambled siRNA + post-C | 9.7 ± 0.5 |
Atg5 and Atg7 siRNA + post-C | 7.3 ± 0.4* |
Number of INL cells/area | |
Scrambled siRNA + post-C | 2.6 ± 0.01 |
Atg5 and Atg7 siRNA + post-C | 2.2 ± 0.01* |
Number of ONL cells/area | |
Scrambled siRNA + post-C | 5.5 ± 0.02 |
Atg5 and Atg7 siRNA + post-C | 5.2 ± 0.03 |
(A) Mean number of cells/area (± SEM) in retinal ganglion cell (RGC) layer in the ischemic retinae 7 days after ischemia + post-C with scrambled siRNA injected 6 h before post-C compared to the number of cells in the ischemic retinae for Atg5 and Atg7 siRNA injected 6 h before post-C.
* = p < 0.01 vs. scrambled via unpaired t test
(B) Mean number (± SEM) of INL cells/area (μm2; x 100) in the ischemic retinae 7 d after ischemia + post-C with scrambled siRNA injected 6 h before post-C compared to the ischemic retinae for Atg5 and Atg7 siRNA injected 6 h before post-C.
* = p < 0.04 vs. scrambled via unpaired t test
(C) Mean number (± SEM) of ONL cells/area (μm2; x 100) in the ischemic retinae 7 days after ischemia + post-C with scrambled siRNA injected 6 h before post-C compared to the ischemic retinae for Atg5 and Atg7 siRNA injected 6 h before post-C.