Figure 6.
The levels of T cell responses were lower in PBMC and lung upon H1N1 infection during the convalescent stage of SARS-CoV-2 infection (a, b) CD3 cells in PBMC (a) and lung (b) in the mice upon H1N1 exposure on 7 and 14 dpi of SARS-CoV-2 infection and in the mice without SARS-CoV-2 infection were detected during H1N1 infection. The data were shown by percentages. (c) The level of TREG cells in PBMC on 4 dpi after H1N1 infection in the mice upon H1N1 exposure on 7 and 14 dpi of SARS-CoV-2 infection and in the mice without SARS-CoV-2 infection were showed. The data were shown by percentages. (d) The levels of Th17 cells, Th1 cells and Th2 cells in the lung on 4 dpi in the mice upon H1N1 exposure on 7 and 14 dpi of SARS-CoV-2 infection and in the mice without SARS-CoV-2 infection were showed. The data were shown by percentages. (e) CD4+ H1N1-HA-tetramer cells in lung of the mice upon H1N1 exposure on 7 and 14 dpi of SARS-CoV-2 infection and in the mice without SARS-CoV-2 infection were showed. n = 3 in every point and the data were analysed using GraphPad Prism 8, and the P-values were calculated by one-way ANOVA using SPSS PASW statistical software version 18.0. *0.01 < P ≤ 0.05, **0.001 < P ≤ 0.01, and ***P ≤ 0.001.