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. 2021 Jun 15;16(6):e0252836. doi: 10.1371/journal.pone.0252836

Table 5. Vaccine type availability and factors that influence choice of vaccine type by the GP in 2019/2020, by risk group, Italy.

ITALY 10-17y with chronic conditions 18-64y with chronic conditions ≥65y 65-74y ≥75y
n (%) n (%) n (%) n (%) n (%)
Vaccine types available (N = 139) (N = 116) (N = 116)
1 110 (79.1) 91 (78.4) 35 (31.0) - -
>1 29 (20.9) 25 (21.6) 81 (69.8) - -
>1 excluding aTIV - - 4 (3.4) - -
>1 including aTIV - - 77 (66.4) - -
Frequency with which GP chooses aTIV a (N = 77) (N = 76)
Always - - - 8 (10.4) 21 (27.6)
Usually - - - 31 (40.3) 44 (57.9)
Sometimes - - - 23 (29.9) 5 (6.6)
Not usually - - - 13 (16.9) 6 (7.9)
Never - - - 2 (2.6) 0 (0)
The following factors influence choice of vaccine type by the GPb QIVe vs QIVc (N = 4) aTIV vs. QIVe and/or QIVc (N = 77) aTIV vs. QIVe and/or QIVc (N = 76)
Patient preference (N = 28; 24; 4) c 3 (10.7) 4 (16.7) 0 (0) 14 (18.2) 15 (19.7)
Directed by vaccine availability (N = 28; 23; 4) c 18 (64.3) 16 (69.6) 4 (100) 55 (71.4) 56 (73.7)
Patient characteristics (N = 26; 24; 4) c 9 (34.6) 12 (50.0) 4 (100) 60 (77.9) 52 (68.4)
The following patient characteristics influence choice of vaccine type by the GPd (N = 8) (N = 11) (N = 4) (N = 60) (N = 52)
Younger age 4 (50.0) 3 (27.3) 1 (25.0) 13 (21.7) 12 (23.1)
Older age 7 (87.5) 8 (72.7) 1 (25.0) 50 (83.3) 42 (80.8)
Presence of multiple comorbidities 4 (50.0) 8 (72.7) 3 (75.0) 47 (78.3) 40 (76.9)
Presence of specific comorbidities 1 (12.5) 0 (0.0) 0 (0.0) 15 (25.0) 11 (21.2)
Higher severity of comorbidities 1 (12.5) 4 (36.4) 2 (50.0) 18 (30.0) 16 (30.8)
Frailty 3 (37.5) 4 (36.4) 1 (25.0) 29 (48.3) 22 (42.3)
Profession - 3 (27.3) - -
Other 1 (12.5) 1 (9.1) 0 (0.0) 7 (11.7) 7 (13.5)

aTIV: adjuvanted trivalent influenza vaccine; n: number of GPs that chose a particular answer; N: number of GPs that answered the question; QIVe: egg-based quadrivalent influenza vaccine; QIVc: cell-based quadrivalent influenza vaccine.

a This question was only posed to GPs that answered “>1 including aTIV” to the first question.

b This question was only posed to GPs that answered “>1 type” to the first question.

c Number of GPs that answered the question for the risk groups 10-17y with chronic conditions, 18-64y with chronic conditions, and ≥65y, respectively.

d This question was only posed to GPs that answered “patient characteristics” to the previous question.