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. 2021 Jun 3;17(6):e1009649. doi: 10.1371/journal.ppat.1009649

Fig 6. Effects of endogenous venestatin on cytokine production in mouse skin tissues.

Fig 6

Quantitative RT-PCR analysis of pro-inflammatory molecules from skin tissues of wild-type (WT) or RAGE-null (RAGE-/-) mice was performed. Total RNA was extracted from mouse skin tissues at the larva inoculation site at 6 h p.i. with 2,000 LL3s treated with dsluciferase (CR) or dsvenestatin (KD). The mouse GADPH gene was used to normalize the amount of cDNA, and the expression level in naïve skin (no larva) was set as 1. Data are expressed as means ± SDs of three independent experiments with two technical replicates. *p < 0.01; **p < 0.001; ***p < 0.0001.