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. 2021 Jun 3;15(6):e0008639. doi: 10.1371/journal.pntd.0008639

Fig 4. The application of the standard WHO larval assay to detect deltamethrin resistance in Ae. aegypti.

Fig 4

Deltamethrin was tested over a range between 5.0 x 10−10 M to 1.0 x 10−6 M. (A) The concentration-response curves are given for the wild-type New Orleans strain (blue) and the Deltamethrin-resistant Cayman strain (red). (B) The fitted PIC50s estimated from fitting the curves in A to a Sigmoid curve. The WHO assay yielded LC50s of 8.60 ± 0.04 (2.5 nM) and 7.29 ± 0.14 (51.3 nM) for New Orleans and Cayman respectively (2-tailed, independent t-test, T(4) = -3.9, P = 0.0). Each point in (B) represents the mean of 3 (WHO) separate experiments and error bars indicate the standard error of the mean.