Skip to main content
. 2021 Jun 15;35(10):2784–2798. doi: 10.1038/s41375-021-01307-0

Fig. 6. LONA overexpression reduces survival in vivo.

Fig. 6

Kaplan–Meier survival curves of NSG mice transplanted with (A) OCI-AML3, (B) OCI-AML2, or (C) OCI-AML2 + NPM1c + cells overexpressing LONA (PIG LONA) or control AML cells (PIG EMPTY). In total 2 × 106 cells were injected in the tail vein of NSG mice. Seven mice were injected per group. Mice were sacrificed when body weight was reduced by >20% or for signs of morbidity. Log rank test for 7 mice per group.