Table 2. MIC Values of Meropenem (MEM)-SPC Combination against NDM-1 Producing Enterobacteriaceae.

strain				MIC (μg mL–1)
	species, genotype	MEM	[I] (μg mL–1)	MEM VNRXa	MEM 6a	MEM 6b	MEM 8	MEM 9	MEM 10	MEM 11	MEM 12	MEM 13	MEM 14
IR57	E. coli	64	0.5		1	1	0.5	1	1	1.5	4	4	1.5
	blaNDM-1		2		≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.375	≤0.25	0.5	≤0.25
			8	0.5	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.375	0.5	≤0.25
B68-1	K. pneumoniae	64	0.5		0.5	0.5	0.5	0.5	1	1	16	1	3
	blaNDM-1		2		≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25
			8	0.5	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.5	0.5	0.5	≤0.25
S117	E. coli	256	0.5		4	2	1	1	1.5	1.5	32	8	4
	blaNDM-1		2		≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.5	≤0.25
			8	1	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.5	0.5	0.5	≤0.25
IR43	K. pneumoniae	128	0.5		≤0.25	≤0.25	0.375	0.5	0.5	0.5	16	0.5	1.5
	blaNDM-1		2		≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25
			8	0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	0.375	0.5	≤0.25

^aMIC values of meropenem (MEM) and VRNX were at 10 μg mL^–1.⁴¹ MIC experiments were repeated in triplicate.