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. 2021 Apr 5;4(3):1195–1203. doi: 10.1021/acsptsci.1c00062

Table 2. Comparison of 9L, U87 ΔEGFR, and DU145 Cell Uptake of [18F]5, anti-cis-3,4-[18F]-DFACPC, syn-cis-3,4-[18F]-DFACPC, and anti-3-[18F]-FACBC without Inhibitors after 30 min of Incubationa.

tracer 9L U87 ΔEGFR DU145
[18F]5 23.5 ± 1.5 6.45 ± 0.46 34.0 ± 4.1
anti-cis-3,4-[18F]-DFACPC 23.4 ± 3.0 7.53 ± 1.2 17.7 ± 3.0
syn-cis-3,4-[18F]-DFACPC 7.82 ± 0.37 4.29 ± 0.29 12.2 ± 0.46
anti-3-[18F]-FACBC 23.2 ± 2.6 6.19 ± 1.22 20.2 ± 3.4
a

Data are presented as percent ligand uptake of the initial dose per 0.5 million cells (%ID/5 × 105 cells) ± standard deviation (n = 3–4) and normalized for the dose and number of cells.