Table 2. Comparison of 9L, U87 ΔEGFR, and DU145 Cell Uptake of [18F]5, anti-cis-3,4-[18F]-DFACPC, syn-cis-3,4-[18F]-DFACPC, and anti-3-[18F]-FACBC without Inhibitors after 30 min of Incubationa.
tracer | 9L | U87 ΔEGFR | DU145 |
---|---|---|---|
[18F]5 | 23.5 ± 1.5 | 6.45 ± 0.46 | 34.0 ± 4.1 |
anti-cis-3,4-[18F]-DFACPC | 23.4 ± 3.0 | 7.53 ± 1.2 | 17.7 ± 3.0 |
syn-cis-3,4-[18F]-DFACPC | 7.82 ± 0.37 | 4.29 ± 0.29 | 12.2 ± 0.46 |
anti-3-[18F]-FACBC | 23.2 ± 2.6 | 6.19 ± 1.22 | 20.2 ± 3.4 |
Data are presented as percent ligand uptake of the initial dose per 0.5 million cells (%ID/5 × 105 cells) ± standard deviation (n = 3–4) and normalized for the dose and number of cells.