. 2021 Apr 5;4(3):1195–1203. doi: 10.1021/acsptsci.1c00062

Table 3. Biodistribution as Percent of Injected Dose Per Gram (%ID/g) of Radioactivity in Tissues of 9L Tumor-Bearing Fischer Rats Following Intravenous Administration of [¹⁸F]5^a.

tissue	4.5 min	12.5 min	52.5 min
liver	1.36 ± 0.14	0.97 ± 0.09	0.62 ± 0.05
heart	1.42 ± 0.10	0.98 ± 0.12	0.67 ± 0.08
lung	0.84 ± 0.08	0.64 ± 0.06	0.59 ± 0.11
muscle	0.56 ± 0.15	0.61 ± 0.12	0.68 ± 0.12
brain	0.39 ± 0.03*	0.43 ± 0.04*	0.46 ± 0.05*
tumor	1.00 ± 0.22*	1.20 ± 0.43*	1.11 ± 0.40*
bone	0.68 ± 0.23	0.75 ± 0.16	0.80 ± 0.09
spine	0.80 ± 0.26	0.75 ± 0.11	0.75 ± 0.15
T/N	2.6	2.8	2.4

Data are reported as mean percent dose per gram ± standard deviation (n = 4) at each time point. p-Values represent comparisons of uptake in the 9L tumor and normal brain using two-tailed paired t-tests. p < 0.05 is considered statistically significant. *p < 0.05.

T/N denotes tumor to brain ratio.

Table 3. Biodistribution as Percent of Injected Dose Per Gram (%ID/g) of Radioactivity in Tissues of 9L Tumor-Bearing Fischer Rats Following Intravenous Administration of [18F]5a.

Table 3. Biodistribution as Percent of Injected Dose Per Gram (%ID/g) of Radioactivity in Tissues of 9L Tumor-Bearing Fischer Rats Following Intravenous Administration of [¹⁸F]5^a.