Table 4. Biodistribution as Percent of Injected Dose Per Gram (%ID/g) of Radioactivity in Tissues in Normal Fischer Rats Following Intravenous Administration of [18F]5a.
| tissue | 10.4 min | 35.6 min | 53.4 min |
|---|---|---|---|
| liver | 1.20 ± 0.25 | 0.64 ± 0.22 | 0.71 ± 0.13 |
| heart | 0.97 ± 0.25 | 0.68 ± 0.14 | 0.66 ± 0.18 |
| lung | 0.73 ± 0.17 | 0.66 ± 0.32 | 0.55 ± 0.10 |
| kidney | 3.99 ± 0.16 | 2.14 ± 0.79 | 2.54 ± 0.64 |
| bladder | 0.65 ± 0.27 | 4.94 ± 2.96 | 9.89 ± 3.05 |
| muscle | 0.42 ± 0.11 | 0.59 ± 0.17 | 0.61 ± 0.18 |
| brain | 0.45 ± 0.13 | 0.49 ± 0.10 | 0.54 ± 0.16 |
| bowel | 0.59 ± 0.02 | 0.37 ± 0.02 | 0.37 ± 0.06 |
| testes | 0.50 ± 0.16 | 0.54 ± 0.21 | 0.50 ± 0.16 |
| bone | 0.76 ± 0.22 | 0.62 ± 0.12 | 0.65 ± 0.17 |
| spine | 0.72 ± 0.17 | 0.65 ± 0.08 | 0.66 ± 0.13 |
Data are reported as mean percent dose per gram ± standard deviation (n = 3) at each time point.