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. 2021 Apr 5;4(3):1195–1203. doi: 10.1021/acsptsci.1c00062

Table 4. Biodistribution as Percent of Injected Dose Per Gram (%ID/g) of Radioactivity in Tissues in Normal Fischer Rats Following Intravenous Administration of [18F]5a.

tissue 10.4 min 35.6 min 53.4 min
liver 1.20 ± 0.25 0.64 ± 0.22 0.71 ± 0.13
heart 0.97 ± 0.25 0.68 ± 0.14 0.66 ± 0.18
lung 0.73 ± 0.17 0.66 ± 0.32 0.55 ± 0.10
kidney 3.99 ± 0.16 2.14 ± 0.79 2.54 ± 0.64
bladder 0.65 ± 0.27 4.94 ± 2.96 9.89 ± 3.05
muscle 0.42 ± 0.11 0.59 ± 0.17 0.61 ± 0.18
brain 0.45 ± 0.13 0.49 ± 0.10 0.54 ± 0.16
bowel 0.59 ± 0.02 0.37 ± 0.02 0.37 ± 0.06
testes 0.50 ± 0.16 0.54 ± 0.21 0.50 ± 0.16
bone 0.76 ± 0.22 0.62 ± 0.12 0.65 ± 0.17
spine 0.72 ± 0.17 0.65 ± 0.08 0.66 ± 0.13
a

Data are reported as mean percent dose per gram ± standard deviation (n = 3) at each time point.