Table IV.
Multivariate∗ analysis for the association between steroids use and COVID-19 severity (moderate-severe) among adult asthmatic patients with positive PCR test result for SARS-CoV-2, using different specifications of steroid use (n = 8242)
| Variable | Adjusted∗ HR (95% CI) | P value |
|---|---|---|
| Steroids use in the previous year | ||
| None | Reference | |
| Yes | 1.49 (1.24-1.79) | <.001 |
| Steroids use in the previous year | ||
| None | Reference | |
| Recent (≤120 d) | 1.92 (1.55-2.38) | <.001 |
| Former (120-365 d) | 1.16 (0.87-1.43) | .390 |
| Chronic steroids treatment (≥6 prescriptions in the previous year) | ||
| None | Reference | |
| Yes | 2.19 (1.63-2.94) | <.001 |
| Steroids use in the previous year (no. of filled prescriptions) | ||
| None | Reference | |
| 1 prescription | 1.06 (0.81-1.39) | .655 |
| 2 prescriptions | 1.54 (1.10-2.15) | .012 |
| ≥3 prescriptions | 2.09 (1.65-2.65) | <.001 |