Table E4.
Multivariate analysis for the association between biologics use and all-cause mortality within 90 d following PCR test date among adult asthmatic patients with positive PCR test result for SARS-CoV-2 (n = 8242)
| Variable | Adjusted∗ HR (95% CI) | P value |
|---|---|---|
| Age (for each year increase) | 1.11 (1.09-1.12) | <.001 |
| Sex | ||
| Males | 1.63 (1.14-2.33) | .008 |
| Females | Reference | |
| Ethnicity | ||
| Jews | Reference | |
| Arabs | 1.07 (0.71-1.63) | .723 |
| Diabetes | 1.73 (1.22-2.47) | .002 |
| Hypertension | 1.44 (0.87-2.37) | .154 |
| Obesity | 1.12 (0.79-1.59) | .514 |
| IHD | 1.85 (1.31-2.60) | <.001 |
| Smoking (ever) | 0.74 (0.50-1.09) | .124 |
| Steroids use in the previous year (no. of filled prescriptions) | ||
| None | Reference | |
| 1 prescription | 0.91 (0.53-1.56) | .733 |
| 2 prescriptions | 0.86 (0.42-1.78) | .694 |
| ≥3 prescriptions | 1.64 (1.05-2.59) | .032 |
| Biologics use (at least 1 prescription filled in the previous 120 d) | ||
| None | Reference | |
| Yes | 1.04 (0.14-7.59) | .969 |
IHD, Ischemic heart disease.
∗
Adjusted for age, sex, ethnicity, diabetes, hypertension, IHD, obesity, smoking, and steroids and biologics use.