PCoA of the Sorensen distances for the 12M-old microbiota (p = 0.003). The comparison is across infants without human milk exposure, with human milk exposure at 6M timepoint only, and human milk exposure at both 6M and 12M. A principal coordinates analysis plot represents each microbial community from a given sample as a single point on a plot with axes that account for the major difference-driving factors. Sorensen distance accounts for the presence or absence of bacterial types between samples. The farther apart the points on the plot, the more dissimilar the samples. Abbreviations: 6M: 6 months, 12M: 12 months, HM: Human Milk, PCoA: Principal Coordinates Analysis.