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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Nat Cancer. 2021 May 17;2(5):503–514. doi: 10.1038/s43018-021-00208-6

Extended Data Fig. 5|. MHCI levels in KL and KP tumors.

Extended Data Fig. 5|

a. MHCI levels from KP or KL allograft tumors as quantified as median fluorescent intensity (MFI) (left). Right, representative histograms depict MHCI level from mice with KP and KL tumors. n=5 tumors each group. (mean±sd, two-sided t test, unpaired) b. MHC I levels from KP or KL tumor cell lines stimulated with IFNγ as shown MFI levels. Left panel, representative histograms. Right panel, quantification of MHC I expression levels in KP and KL after IFNγ (100ng/ml) stimulation for 18 hrs. n=3 cell cultures each group. Shown representative result of three independent experiments (mean±sd, multiple t test, FDR<0.05). c. MHC I subunit H-2K and H-2D levels change in response to ULK1 inhibitor MRT68921 in mouse KL line in vitro 48hrs after the treatment. Data representative of two independent experiments.