Figure 3. Subgroup Analyses of the Probability of Functional Independence (mRS Score 0–2) at 90 Days According to the History of IV tPA Pretreatment.

Bridging therapy was associated with a significantly higher odds of functional independence in patients with NIH Stroke Scale (NIHSS) score <15 and ischemic core <50 cm³, whereas no significant difference in functional independence was observed in patients with NIHSS score ≥15 and ischemic core ≥50 cm³. Effect of tissue plasminogen activator (tPA) was more pronounced in patients who were transferred to the endovascular thrombectomy (EVT)–capable center compared to patients who presented directly. CI = confidence interval; OR = odds ratio.