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. 2021 Jun 11;12:449–463. doi: 10.2147/JBM.S271744

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© 2021 Mathews et al.

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Diagnostic algorithm for GT. *Consider proceeding to platelet light transmission aggregometry if suspicion for platelet defect remains high. **Consider genetic testing to identify specific mutation of ITGA2B and ITGB3 and/or flow cytometry to differentiate GT type. ^†Consider clot retraction assay (if available) and platelet light transmission aggregometry or genetic testing of ITGA2B and ITGB3 to make the diagnosis of GT Type III. ^††Consider genetic testing to identify specific mutation of ITGA2B or ITGB3.

Abbreviations: CBC, complete blood count; VWF Ag, von Willebrand factor antigen; VWF Act, von Willebrand factor activity; VWD, von Willebrand disease.