Table A2.
Standardized effect of no treatment and definitive chemoradiation, compared to surgery, on 5-year mortality among nonmetastatic adult esophageal cancer cases who survived ≥12 months after diagnosis, stratified by stage
| HR (95% CI)† | P-value | |
|---|---|---|
| STAGE I | ||
| No treatment | 1.52 (1.33, 1.74) | <0.0001 |
| Definitive chemoradiation | 3.04 (2.75, 3.37) | <0.0001 |
| Surgery (with or without chemoradiation) | REF | – |
| STAGE II | ||
| No treatment | 1.41 (1.13, 1.75) | 0.0021 |
| Definitive chemoradiation | 1.57 (1.47, 1.67) | <0.0001 |
| Surgery (with or without chemoradiation) | REF | – |
| STAGE III | ||
| No treatment | 1.75 (1.45, 2.12) | <0.0001 |
| Definitive chemoradiation | 1.58 (1.49, 1.67) | <0.0001 |
| Surgery (with or without chemoradiation) | REF | – |
† Standardized across clinical cancer stage, year of diagnosis, age (modeled as a restricted cubic spline), sex, Charlson–Deyo score, race, primary insurance, travel distance to hospital, median household income, and education.
CI, confidence interval; HR, hazard ratio.