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. 2020 Oct 29;223(12):2090–2098. doi: 10.1093/infdis/jiaa677

Figure 3.

Figure 3.

Locus zoom plot of the significance P value for the X chromosome multiancestry meta-analysis of all individuals (male and female), showing suggestively associated markers in the ChrXq24 region. Each point represents a single-nucleotide polymorphism (SNP) passing quality control, plotted with its P value as a function of genomic position (Genome Reference Consortium Human genome build 37 assembly). The lead SNP is represented by the purple symbol. The color coding of all other SNPs indicates linkage disequilibrium with the lead SNP estimated by r2 values for European populations of the 1000 Genomes Project (red, r2 ≥ 0.8; gold, 0.6 ≤ r2 < 0.8; green, 0.4 ≤ r2 < 0.6; cyan, 0.2 ≤ r2 < 0.4; blue, r2 < 0.2; gray, r2 unknown. Abbreviations: AC005052.1, Homo sapiens BAC clone CTB-38K21 from Xq23; MIR766, microRNA 766; RPL39, ribosomal protein L39; SEPT6, septin 6; SNORA69, small nucleolar RNA; SOWAHD, Sosondowah Ankyrin repeat domain family member D, H/ACA box 69.