Table 2.

Outcomes in the Key PUL Trials

Study	Factors/Outcomes Measured	Major Results
L.I.F.T. study16	Measured IPSS, QoL, Qmax, BPHII, IIEF-5, MSHQ-EjD function/bother after PUL treatment for LUTS due to BPH with lateral lobe obstruction	Significant and durable improvement in IPSS, QoL, Qmax, BPHII without impairment of sexual function through 5 years.
MedLift study18	Expanded on L.I.F.T. study design by using participants treated with PUL due to BPH with median lobe obstruction	Similarly to the L.I.F.T. study, participants saw an improvement in IPSS, QoL, Qmax, BPHII without impairment of sexual function through 1 year.
BPH6 study21	BPH6 index was used to measure composite of the following: symptom relief, quality of recovery, erectile function preservation, continence preservation, and safety. Additional factors measured: Patient perspective Quality of life Sleep quality	Compared to TURP, PUL resulted in higher quality recovery, preservation of ejaculatory function, and higher overall BPH6 index. TURP resulted in significantly compromised urinary continence function 2 weeks and 3 months following procedure. PUL resulted in superior improvement of sleep compared to TURP.
2-Year Outcomes of a Retrospective Multicenter Study24	IPSS QoL Qmax Age Prostate size Site of service Prior prostate cancer treatment Diabetic status	Significant improvement in IPSS throughout two years following PUL. Subjects with IPSS greater than or equal to 13 exhibited similar results to L.I.F.T. study. Age, diabetic status, prostate volume, site of service, a prior cancer therapy did not affect outcomes of PUL. Subjects were older in age and less symptomatic than those included in L.I.F.T. study.