Table 2.
Mass spectrometry parameters of drugs and corresponding SIL-ISs
| Drug name | Precursor ion (m/z) | Product ion (m/z) | De-clustering potential DP (V) | Collision pressure CE (eV) |
|---|---|---|---|---|
| ARI | 448.03 | 285.10 | 54 | 26 |
| ARI-d8 | 456.03 | 293.15 | 54 | 26 |
| AMI | 370.07 | 241.97 | 54 | 26 |
| AMI-d5 | 375.08 | 241.98 | 52 | 27 |
| OLA | 313.03 | 256.05 | 48 | 22 |
| OLA-d3 | 316.07 | 256.06 | 42 | 22 |
| PAL | 427.10 | 207.11 | 50 | 28 |
| PAL-d4 | 430.90 | 211.04 | 52 | 28 |
| ZIP | 412.97 | 194.03 | 54 | 30 |
| ZIP-d8 | 420.99 | 193.90 | 56 | 30 |
Note: SIL-IS: stable isotope labeled internal standard; ARI: Aripiprazole; AMI: Amisulpride; OLA: Olanzapine; PAL: Paliperidone; ZIP: Ziprasidone.