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. 2021 May 15;13(5):4167–4181.

Figure 5.

Figure 5

Over-expressed miR-122-5p aggravated BMECs injury. A: miR-122-5p expression in un-induced and LPS-induced neutrophil exosomes; B: miR-122-5p expression in BMECs detected by RT-qPCR; C: Cell proliferation detected by CCK-8; D: Clone formation assay results; E: Clone cell number; F: Expressions of antioxidant substances (SOD and CAT); G: ROS expression; H: MDA expression. Compared with the neutrophil EXOs group, &P<0.05; compared with the control group, %P<0.05; compared with the miR-NC-exo group, @P<0.05. RT-qPCR: real-time quantitative polymerase chain reaction; CCK-8: cholecystokinin octopeptide; LPS: lipopolysaccharide; ROS: reactive oxygen species; MDA: malondialdehyde; SOD: superoxide dismutase; CAT: catalase; NC: negative control.