Figure 2.

Overexpressing HDAC4 can partially reverse JAT’s protective effect on SH-SY5Y cells. A, B: Expression of HDAC4 in each group of cells; C: Cell proliferation is tested by MTT assay; D, E: Apoptosis is tested by flow cytometry; F-H: Detection results of OS parameters (MDA, LDH and SOD). Compared with control group, *P<0.05, compared with AD group, &P<0.05, while compared with AD+JAT+pcDNA3.1-NC group, ^P<0.05. JAT: Jatrorrhizine; MDA: malondialdehyde; LDH: lactate dehydrogenase; SOD: superoxide dismutase.