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. 2021 May 18;27(6):1071–1078. doi: 10.1038/s41591-021-01370-1

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© The Author(s) 2021

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Fig. 2 — Participants were monitored for solicited local (a) and systemic (b) AEs from the time of vaccination through 7 d after vaccine administration. There was no grade 4 (potentially life-threatening) event. Participants who reported no AEs make up the remainder of the 100% calculation (data not shown). If any of the solicited AEs persisted beyond Day 7 after each vaccination (when applicable), it was recorded as an unsolicited AE. Fever was defined as oral temperature ≥38.0 °C.