Fig. 11.

Representative localization of SMN in the ventral root of the lumbar spinal cord from WT and SMA mice. Electron micrograph of cross-section of the ventral root of the lumbar spinal cord from WT mouse a showing numerous SMN immuno-gold particles (arrows). b Only few SMN immuno-gold particles (arrows) are detected in the ventral root of the lumbar spinal cord from SMA mouse. c The graph reports the number of SMN immuno-gold particles in SMA and WT mice. Values are the mean number ± S.E.M. of 200 axons of the ventral root per group. Scale bar: a, b = 0.2 µm. *P ≤ 0.05 compared with WT