Table 3.
Diagnostic performance
| Parameter | cut-off value‡ | TP | TN | FP | FN | Accuracy | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| Binary CE | 22 | 28 | 4 | 19 | 0.68 (0.57–0.79) | 53.7 (37.4–69.3) | 87.5 (71.0–96.5) | 84.6 (67.8–93.5) | 59.6 (50.8–67.7) | |
| Decision tree 1 (LPDI & CEbin) | 28 | 28 | 4 | 13 | 0.77 (0.65–0.86) | 68.3 (51.9–81.9) | 87.5 (71.0–96.5) | 87.5 (71.0–96.5) | 68.3 (51.9–81.9) | |
| Decision tree 2 (LPDI & CEvol) | 34 | 27 | 5 | 7 | 0.84 (0.73–0.91) | 82.9 (67.9–92.8) | 84.4 (67.2–94.7) | 87.2 (72.6–95.7) | 79.4 (62.1–91.3) | |
| Hepatic AAST± | 2 (1 vs. 2–5) | 41 | 0 | 31 | 0 | 0.57 (0.45–0.69) | 100 (91.4–100.0) | 0 (0 –11.2) | 56.9 (56.9–56.9) | -†† |
| 3 (1–2 vs. 3–5) | 40 | 5 | 26 | 1 | 0.63 (0.50–0.74) | 97.6 (87.1–99.9) | 16.1 (5.5–33.7) | 60.6 (56.7–64.4) | 83.3 (38.1–97.6) | |
| 4 (1–3 vs. 4–5) | 27 | 16 | 15 | 14 | 0.60 (0.47–0.71) | 65.9 (49.4–79.9) | 51.6 (33.1–69.8) | 64.3 (54.1–73.4) | 43.5 (41.2–45.8) | |
| 5 (1–4, vs. 5) | 2 | 30 | 1 | 39 | 0.44 (0.33–0.57) | 4.9 (0.6–16.5) | 96.8 (83.3–99.9) | 66.7 (16.0–95.5) | 43.5 (41.2–45.8) | |
Note.—
±
For hepatic AAST organ injury scale, accuracy metrics are shown for each categorical grade (n =72). One subject was excluded due to missing Hepatic AAST grade
††
NPV not defined because no data is classified as test negative at the specified threshold.
‡
value ≥ cut-off value is defined as test positive
Abbreviations: PPV- positive predictive value, NPV, negative predictive value, LPDI- liver parenchymal disruption index, CE- contrast extravasation, CEbin- contrast extravasation binary, CEvol- contrast extravasation volume, AAST- American Association for the Surgery of Trauma