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. Author manuscript; available in PMC: 2022 Jun 15.
Published in final edited form as: Biomater Sci. 2021 Jun 15;9(12):4260–4277. doi: 10.1039/d0bm01497d

Figure 7: Characterization of mExo-siRNA loaded via ExoFect and Lipofectamine.

Figure 7:

(A) Comparison of relative efficiencies of intra-luminal siRNA loading into mExo using two chemical transfection reagents, ExoFect and Lipofectamine-2000 (* vs Lipofect only, # vs ExoFect only, $ vs mExo only; p<0.05). (B) Optimization of mExo siRNA loading using Lipofect. (C) Change in particle surface charge following siRNA loading by ExoFect and Lipofectamine. (D) Change in particle size following loading by both methods. Data are presented as mean ± 95% bootstrap confidence intervals (* vs 0.8% Lipofect:mExo (% v/v); p<0.05).