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(A) Dose-dependent response of exosome-mediated GFP silencing, compared to residual Lipofect-siRNA complexes left over from the purification process. (B) Comparison of silencing between unmodified and PEGylated mExo. (C) Fluorescence microscopy imaging showing silencing of GFP in confluent HEK293 cells. White scale bar represents 100 μm. (* vs Control, # vs mExo-siRNA; p<0.05).
