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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Laryngoscope. 2021 Jan 12;131(7):E2125–E2130. doi: 10.1002/lary.29385

Fig. 1.

Fig. 1.

Animal experiment flow chart and histologic assessment of iLTS mice. (A) iLTS surgery was performed at day −4. PBS and DON treatments were started 4 days after surgery and were i.p. administrated to mice every other day. Laryngotracheal complexes were harvested at days 7 and 14. (B) DON treatment significantly reduced the fibrotic lamina propria thickness in iLTS mice compared with PBS group at days 7 and 14. Quantification of the lamina propria thickness measurement from the histological results is shown in (C). (*) = P < .05; i.p.: Intraperitoneal injection; DON: 6-Diazo-5-oxo-L-norleucine; LP: lamina propria; C: cartridge; E: epithelial cells. Scale bar: 100 um.