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. Author manuscript; available in PMC: 2022 Jul 12.
Published in final edited form as: Biochem Biophys Res Commun. 2021 May 27;562:133–138. doi: 10.1016/j.bbrc.2021.05.057

Figure 3. YAP regulated transcripts TEAD4 and XIAP are induced during C. trachomatis infection in a Tarp-dependent manner.

Figure 3.

HeLa cells were infected with C. trachomatis L2 (WT), a tarP deletion mutant (Δtarp), or the mutant complemented with pTarp (Δtarp + pTarp). Mock infected cells (uninfected) served as the negative control. RNA was harvested from uninfected or infected cells 8 hours post infection. Data are presented as the relative fold change in transcriptional enhancer factor TEF 4 (TEAD4) and X-linked inhibitor of apoptosis protein (XIAP) mRNA levels in infected versus uninfected cells normalized to GAPDH transcripts. Statistical analysis was performed using a one-way analysis of variance (ANOVA) followed by Dunnett’s multiple comparisons test to the uninfected control (** p<0.01, ***p<0.001, **** p<0.0001).