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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Exp Cell Res. 2021 May 26;405(1):112663. doi: 10.1016/j.yexcr.2021.112663

Figure 3. Exosomes from culture-activated mouse HSCs stimulate IL-6 and TNFα production in macrophages.

Figure 3.

Exosomes (EXOs) from day 14 culture-activated mouse HSCs were added to culture medium of mouse (RAW 264.7) macrophages for 24 or 48 hours. Macrophages were analyzed for A) IL-6 mRNA expression and B) TNF-α mRNA expression. Culture medium was analyzed for C) IL-6 protein secretion and D) TNF-α protein secretion. *P<0.05 versus control (C), #P<0.05 versus LPS only, n=4 independent experiments.