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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: Genesis. 2021 Apr 14;59(5-6):e23419. doi: 10.1002/dvg.23419

FIGURE 6.

FIGURE 6

Different limb phenotypes in L35 and A11 mouse lines driven by Prrx1-Cre. Both line L35 and A11 were bred with the Prrx1-Cre mouse line and embryos were harvested at the stages indicated. Skeletal patterns in limbs were visualized either by whole mount cartilage staining (E14.5) or Alcian blue/alizarin red staining (PN20). Bar = 400 μm (A1, B1, C1), 1 mm (A, B, C), or 2 mm (D-I, J-K). For PN20, the length of each segment of limbs are normalized by length of the spine (from cervical 1 to sacral 4) and compared between two genotypes (6L, M). Au, autopod, Ze, zeugopod, St, stylopod, Sc, scapula. N=3. ***, p<0.001.