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. 2021 Jun 15;12(6):617. doi: 10.1038/s41419-021-03891-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Heatmap illustrating the 20 differentially regulated lncRNAs between two pairs of tumor tissues and corresponding adjacent tissuesfrom PTC patients (fold change >2, p < 0.05). The mark in red denotes lncRNA OIP5-AS1. B, C Representative OIP5-AS1 and ADAMTS8 expression in tumor sections of 72 patients with PTC were detected by qRT-PCR. D Pearson correction of OIP5-AS1 and ADAMTS8 were analysed (n = 72). E, F Survival rate of PTC patients was analyzed by Kaplan–Meier method. Log-rank tests were used to determine statistical significance. ***p < 0.001.