Table 1.
Characteristics of the TOPMed samples by study
| Study | N (male) | Age | HCT | HGB | MCH | MCHC | MCV | RBC | RDW |
|---|---|---|---|---|---|---|---|---|---|
| Amish | 1,102 (557) | 50.6 ± 16.9 | 40.6 ± 3.5 | 13.8 ± 1.2 | 30.9 ± 1.3 | 34.1 ± 0.8 | 90.7 ± 3.4 | 4.5 ± 0.4 | – |
| ARIC | 8,113 (3,577) | 54.8 ± 5.8 | 41.6 ± 4.0 | 13.9 ± 1.4 | 30.5 ± 2.1 | 33.3 ± 1.0 | 89.6 ± 5.1 | 4.5 ± 0.5 | 14.1 ± 1.1 |
| BioMe | 10,990 (4,559) | 52.1 ± 13.5 | 39.5 ± 5.2 | 13.1 ± 1.7 | 30.3 ± 2.8 | 33.7 ± 1.0 | 89.0 ± 7.2 | 4.4 ± 0.6 | 14.2 ± 1.8 |
| CARDIA | 3,042 (1,319) | 25.0 ± 3.6 | 42.1 ± 4.4 | 14.2 ± 1.5 | 29.8 ± 2.1 | 33.8 ± 1.0 | 88.1 ± 5.4 | 4.8 ± 0.5 | – |
| CHS | 3,490 (1,459) | 72.6 ± 5.4 | 41.8 ± 3.9 | 14.0 ± 1.3 | – | 33.5 ± 1.0 | – | – | – |
| COPDGene | 5,794 (2,913) | 64.8 ± 8.8 | 42.0 ± 4.1 | 13.9 ± 1.5 | 30.3 ± 2.3 | 33.2 ± 1.1 | 91.4 ± 5.8 | 4.6 ± 0.5 | – |
| FHS | 3,140 (1,514) | 58.4 ± 15.0 | 41.6 ± 4.0 | 14.1 ± 1.3 | 31.1 ± 1.8 | 33.9 ± 1.0 | 91.9 ± 4.9 | 4.5 ± 0.5 | 13.1 ± 1.0 |
| GeneSTAR | 1,713 (699) | 43.7 ± 12.9 | 40.9 ± 3.9 | 13.5 ± 1.4 | 29.6 ± 2.1 | 33.0 ± 0.8 | 89.5 ± 5.3 | 4.6 ± 0.4 | – |
| HCHS/SOL | 7,655 (3,186) | 46.6 ± 14.0 | 42.1 ± 4.1 | 13.8 ± 1.5 | 29.1 ± 2.2 | 32.7 ± 1.4 | 89.2 ± 6.0 | 4.7 ± 0.4 | 13.8 ± 1.3 |
| JHS | 2,905 (1,089) | 53.5 ± 12.8 | 39.4 ± 4.3 | 13.1 ± 1.5 | 28.9 ± 2.5 | 33.2 ± 0.9 | 86.9 ± 6.3 | 4.5 ± 0.5 | 13.7 ± 1.4 |
| MESA | 2,499 (1,211) | 69.4 ± 9.2 | 40.1 ± 4.0 | 13.4 ± 1.4 | 30.1 ± 2.3 | 33.4 ± 1.1 | 89.9 ± 6.0 | 4.5 ± 0.5 | – |
| SAFS | 1,152 (492) | 40.6 ± 15.9 | 40.3 ± 4.5 | 13.1 ± 1.5 | 29.0 ± 2.3 | 32.6 ± 1.4 | 88.9 ± 5.4 | 4.5 ± 0.5 | – |
| WHI | 10,913 (0) | 66.7 ± 6.8 | 40.2 ± 2.9 | 13.5 ± 1.0 | 29.9 ± 2.1 | 32.9 ± 1.1 | 90.9 ± 5.8 | 4.4 ± 0.4 | 14.2 ± 1.3 |
Values are shown as mean ± SD. Abbreviations are as follows: HCT, hematocrit; HGB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RBC, red blood cell count; RDW, red blood cell width.