Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 15;11:12603. doi: 10.1038/s41598-021-91972-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Spread of the optogenetic activation to V2. (a) fUS activation maps obtained during visual stimulation of the contralateral eye (top) and optogenetic stimulation of the ChrimsonR-expressing ipsilateral V1 area (bottom) and control stimulation of the uninjected contralateral area from a single imaging plane (AP − 7.5 mm) containing the V2 area. White dashed lines delimit the ipsilateral V2 area. Scale bar: 2 mm. (b) Percentage active volume of V2 after visual, optogenetic or control stimulation. For both visual and optogenetic stimulation, we show the volumes of V2 ipsilateral to the injection, whereas, for the control, we shown the volume of the contralateral V2. Open circles represent mean values over all imaging planes for each animal (visual and optogenetic, n = 1, Wilcoxon signed-rank test, one-tailed, p = 0.002, n = 7 for control, Mann–Whitney test, one-tailed, p = 0.0004), bars represent the mean over all animals. (c) SDF of a typical V2 single unit responding to visual (black line) and optogenetic (red line) stimulation of the ipsilateral V1 area. (d) ON latencies of V1 and V2 single-unit responses to visual (V1, n = 33 units, V2, n = 14 units) or optogenetic stimulation of V1 (V1, n = 76 units, V2, n = 8 units). The irradiance used for optogenetic and control stimulation was 140 mW mm⁻².