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. 2021 Jun 2;12:668487. doi: 10.3389/fimmu.2021.668487

Figure 6.

Figure 6

MOG expression in immune organs induces T cell tolerance and suppresses EAE. (A), Analysis of CD4 and CD3 expression in transgenic TCR Vα3.2+Vβ11+ cells after bone marrow transplantation. Representative plots are shown. (B), Mean EAE clinical scores in WT (n = 6) or TgMOG (n = 6) mice immunized with MOG35-55. (C), Mean EAE clinical scores in 2D2 (n = 6) or 2D2 X TgMOG (n = 4) mice immunized with MOG35-55. (B, C), Representative data from two independent experiments is shown. ****P < 0.0001 (Two-way ANOVA).