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. 2021 Jun 2;8:649990. doi: 10.3389/fmolb.2021.649990

FIGURE 4.

FIGURE 4

Surface representation of electronic structure of PS1 Tyr256Ser and Ala260Val mutations: (A) the potential–potential surface of wild type (left) and mutation Tyr256Ser (right). Modification of the surface corresponding to position 256 can be observed; (B) density surface of wild type (left) and mutation Ala260Val (right), showing the increment in charges volume, blocking potential access to Asp257. The space around Tyr256 is used as a point of reference.