Figure 2.

The photos illustrate (own documentation): (A) damage of the marrow which induces IL-6 and release of other stress cytokines whose level is modified by SNP polymorphic features (14, 24, 25, 112, 113), (B) skin biopsy with CD8+ cell epithelium colonization in aGvHD case (114), (C) EBV reactivation documented on 104^th day after transplant (23), (D) macrophages in a patient with hemophagocytic syndrome, the skin biopsy documenting early endothelial cell damage in the patient developing overt thrombotic microangiopathy at a later time.